Related Experiment Video
Updated: Jul 10, 2026
07:50
An In Vitro Model of a Parallel-Plate Perfusion System to Study Bacterial Adherence to Graft Tissues
Published on: January 7, 2019
Bivalvular Bartonella henselae prosthetic valve endocarditis.
Holenarasipur R Vikram1, A Kirstin Bacani, Patrick A DeValeria
1Division of Infectious Diseases, Mayo Clinic (Phoenix Campus), Phoenix, AZ 85054, USA. vikram.hr@mayo.edu
Journal of Clinical Microbiology
|October 19, 2007
Summary
Prosthetic valve endocarditis caused by Bartonella henselae is rare. This case highlights successful treatment of this infection in prosthetic valves using combined medical and surgical approaches.
Area of Science:
- Infectious Diseases
- Cardiology
- Nephrology
Background:
- Prosthetic valve endocarditis (PVE) is a serious complication following valve replacement surgery.
- Infection with Bartonella species, particularly Bartonella henselae, is an infrequent cause of PVE.
Observation:
- A case of PVE involving both prosthetic mitral and aortic valves is presented.
- The patient presented with symptoms that initially suggested Wegener's granulomatosis due to concurrent crescentic glomerulonephritis.
Findings:
- Bartonella henselae was identified as the causative agent of the endocarditis.
- The patient achieved a favorable outcome through a combination of medical management and surgical intervention.
Implications:
- This case underscores the importance of considering Bartonella infection in PVE, even with atypical presentations.
- Successful management strategies for PVE caused by Bartonella henselae involve multidisciplinary approaches, including surgery and targeted antimicrobial therapy.
Related Concept Videos
01:25Endocarditis I: Introduction
Introduction:Endocarditis is the infection of the endocardium, the inner lining of the heart and its valves. When the heart muscle is involved, the condition is termed myocarditis, while an infection of the outer lining is called pericarditis. Infective endocarditis (IE) primarily affects the endocardium, where pathogens adhere to the valves or lining, forming vegetation that can lead to severe complications. Infective endocarditis occurs when microorganisms, usually bacteria from other body...
01:25Endocarditis II: Clinical Features of Infective Endocarditis
Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
01:18Endocarditis III: Medical Management
Infective endocarditis management involves a multifaceted approach encompassing infection prevention, lifestyle modifications, pharmacological therapy, and surgical management.Infection Prevention:Hand Hygiene: Thorough handwashing is crucial to prevent the spread of infection. Hand hygiene should be performed regularly, especially before and after using the restroom.Oral Hygiene: Good oral hygiene is essential. It includes brushing teeth immediately after waking up and before bed, flossing...
01:22Mitral Stenosis I: Introduction
Mitral Valve Stenosis (MVS) is a heart condition where the mitral valve narrows, impeding blood circulation from the left atrium to the left ventricle. The etiology and pathophysiology of this condition are multifaceted, leading to a cascade of cardiovascular complications.Causes of Mitral Valve StenosisRheumatic Heart Disease: It is the main cause of mitral valve stenosis, particularly in developing nations. This condition arises from rheumatic fever, an inflammatory illness resulting from...
01:26Mitral Stenosis III: Medical Management
Mitral stenosis, a condition marked by the narrowing of the mitral valve, necessitates an integrated approach for effective management. This approach includes preventative measures, medical therapy, and surgical interventions to reduce symptoms and prevent complications.PreventionPrevention of mitral stenosis primarily focuses on reducing the incidence of bacterial infections, particularly streptococcal infections, which can lead to rheumatic fever and subsequent valvular damage. Timely...
01:29Endocarditis IV: Nursing Management
Infective endocarditis (IE) is a chronic infection of the heart's endocardium, primarily affecting the heart valves. A detailed nursing assessment for a patient with IE involves collecting subjective and objective data to ensure an accurate diagnosis and timely intervention.Subjective DataThe nurse gathers information about the patient's symptoms and complaints during the subjective assessment. Patients with infective endocarditis often report non-specific symptoms that can mimic other...