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Patch Clamp

Patch Clamp

Many fundamental cell functions such as muscle contraction and nerve transmission rely on the electrical signals produced by the movement of positively and negatively charged ions across the cell membrane. One competent method to record current flowing across the whole cell or single ion channel is the patch-clamp technique.
In this method, a glass micropipette containing electrolyte solution is tightly sealed against a small portion of the cell membrane. As a result, a patch of the cell...

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Related Experiment Video

Updated: Jul 10, 2026

Membrane Transport Processes Analyzed by a Highly Parallel Nanopore Chip System at Single Protein Resolution

Membrane Transport Processes Analyzed by a Highly Parallel Nanopore Chip System at Single Protein Resolution

Published on: August 16, 2016

Cell trapping in activated micropores for functional analysis.

AmirAli H Talasaz¹, Ashley A Powell, Patrik Stahl

¹Electr. Eng. Dept., Stanford Univ., CA 94305, USA. atalasaz@stanford.edu

Conference Proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference

|October 20, 2007

Summary

This summary is machine-generated.

A new device enables high-throughput biochemical assays on single cells, aiding in early cancer diagnosis by screening rare circulating tumor cells. The technology precisely positions and captures individual cells in micropores for functional analysis.

Failed At:

2026-07-10T14:56:53.235339+00:00

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