Contrast enhancement for hypoechoic lesions
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Updated: Jul 10, 2026

Tissue Preparation Techniques for Contrast-Enhanced Micro Computed Tomography Imaging of Large Mammalian Cardiac Models with Chronic Disease
Published on: February 8, 2022
Vincent Laurain1, Dieter Hönigmann
1Adv. Comput. Vision, GmbH, Vienna, Austria. office@acv.ac.at
Abstract:
We propose a novel method for contrast enhancement in hypoechoic lesions. Our approach is based on the concept of distance on image manifolds to obtain a credibility function which captures the delineation of the lesion; if the lesion is sharply defined, the credibility function will also give a sharp response, whereas it varies smoothly at locations where no reliable information about the lesion's perimeter exists due to shortcomings of image acquisition, or because the lesion's border itself is only vaguely defined. The credibility function is used to either increase contrast of the lesion with respect to the adjacent tissue or to stain the lesion by a color overlay.
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