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Updated: Feb 11, 2026

Visualization and Quantification of TGFβ/BMP/SMAD Signaling under Different Fluid Shear Stress Conditions using Proximity-Ligation-Assay
Published on: September 14, 2021
Wall shear stress variations in basilar tip aneurysms investigated with computational fluid dynamics
Christof Karmonik1, Goetz Benndorf, Richard Klucznik
1Methodist Hosp. Res. Inst., Houston, TX 77030, USA. ckarmonik@tmh.tmc.edu
Abstract:
Hemodynamics are thought to play an important role in the creation, thrombosis, recanalization, regrowth and re-bleeding of cerebral aneurysms treated by endovascular means. However, their exact role and interaction is unclear and warrants further study. Towards a systematic classification of the hemodynamics in intracranial aneurysms, we investigated the dependence of the values of the magnitude of the wall shear stresses in the vicinity of the aneurysm on varying inflow conditions in three basilar tip aneurysms.
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