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Updated: Jul 10, 2026
Hollow Microneedle-based Sensor for Multiplexed Transdermal Electrochemical Sensing
Published on: June 1, 2012
Microneedle array for measuring wound generated electric fields
E V Mukerjee1, R R Isseroff, R Nuccitelli
1Center for Micro & Nano Technol., Lawrence Livermore Nat. Lab., CA 94551, USA. mukerjee2@llnl.gov
Abstract:
A microneedle array has been fabricated and applied to the measurement of transdermal skin potentials in human subjects. Potential changes were recorded in the vicinity of superficial wounds, confirming the generation of a lateral electric field in human skin. The measured electric field decays with distance from the wound edge, and is directed towards the wound. The measurement of endogenous fields in skin is a prelude to the study of the therapeutic efficacy of applied electric fields to chronic non-healing wounds.
