Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Interfacial Electrochemical Methods: Overview

Interfacial Electrochemical Methods: Overview

Interfacial electrochemical methods focus on the phenomena occurring at the boundary between an electrode and a solution, as opposed to bulk methods that concentrate on the solution's overall properties. These interfacial methods are classified as either static or dynamic based on the presence of a nonzero current in the electrochemical cell and the consistency of analyte concentrations. Static methods, such as potentiometry, measure the cell's potential without any significant current passing...

Potentiometry: Membrane Electrodes

Potentiometry: Membrane Electrodes

Membrane electrodes, also known as p-ion electrodes, use membranes that selectively interact with free analyte ions, generating a potential difference across the membrane. The resulting membrane potential, known as the asymmetry potential, is not zero even when analyte concentrations on both sides of the membrane are equal. The membrane's response is typically not selective to a single analyte but proportional to the concentration of all ions in the sample solution capable of interacting at the...

Electrochemical Cells

Electrochemical Cells

Electrochemical cells are systems that convert chemical energy into electrical energy or use electrical energy to drive chemical reactions. They consist of two electrodes in contact with an electrolyte, where redox reactions enable electron transfer. Most electrochemical cells include two half-cells connected by an external wire for electron flow and a salt bridge for ion flow. The salt bridge contains an electrolyte solution and maintains charge neutrality by allowing ions—not electrons—to...

Controlled-Potential Coulometry: Electrolytic Methods

Controlled-Potential Coulometry: Electrolytic Methods

Controlled-potential coulometry, also known as potentiostatic coulometry, employs a three-electrode system in which the working electrode's potential is precisely regulated using a potentiostat. Platinum working electrodes are utilized for positive potentials, while mercury pool electrodes are favored for extremely negative potentials. The platinum counter electrode is separated from the analyte using a membrane or salt bridge to avoid interference in the analysis.
The chosen potential ensures...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Electrothermal Oxidation of Ethylene Glycol Over Co<sub>3</sub>O<sub>4</sub>.

Angewandte Chemie (International ed. in English)·2026

Same author

Resolving Microscale Selectivity of Electrochemical CO<sub>2</sub> Reduction Using Hybrid Dual-Probe Scanning Electrochemical Cell Microscopy.

ACS nano·2026

Same author

Coupling Electrochemical CO<sub>2</sub> Reduction With Ethanol Oxidation for Acetate Production in a Dual-Electrolyzer System.

Angewandte Chemie (International ed. in English)·2026

Same author

A Miniaturized Two-Electrode Detection System for Convenient and Rapid Ferricyanide-Mediated Chemical Toxicity Screening.

Analytical chemistry·2026

Same author

Selection and Assessment of Bio-Based Solvent in Biocatalysis: Application to Lipase-Catalyzed Synthesis of Caffeic Acid Phenethyl Ester.

Chembiochem : a European journal of chemical biology·2026

Same author

Compositional and Structural Impact on the Hydrogen Evolution Reaction Activity across Noble-Metal-Based Compositionally Complex Solid Solutions Thin Film Libraries.

ACS electrochemistry·2026

Search research articles

Related Experiment Video

Updated: Jul 10, 2026

A Microfluidic Chip for the Versatile Chemical Analysis of Single Cells

A Microfluidic Chip for the Versatile Chemical Analysis of Single Cells

Published on: October 15, 2013

Single-cell microelectrochemistry.

Albert Schulte¹, Wolfgang Schuhmann

¹School of Chemistry, Institute of Science, Suranaree University of Technology, 111 University Avenue, Muang District, Nakhon Ratchasima 30000, Thailand.

Angewandte Chemie (International Ed. in English)

|October 20, 2007

Summary

This summary is machine-generated.

Voltammetric ultramicroelectrodes offer sensitive detection of cellular activity. These tools enable precise electrochemical measurements near living cells for studying their fundamental functions.

More Related Videos

Microprobe Capillary Electrophoresis Mass Spectrometry for Single-cell Metabolomics in Live Frog (Xenopus laevis) Embryos

Microprobe Capillary Electrophoresis Mass Spectrometry for Single-cell Metabolomics in Live Frog (Xenopus laevis) Embryos

Published on: December 22, 2017

Precise Electrochemical Sizing of Individual Electro-Inactive Particles

Precise Electrochemical Sizing of Individual Electro-Inactive Particles

Published on: August 4, 2023

Related Experiment Videos

Last Updated: Jul 10, 2026

A Microfluidic Chip for the Versatile Chemical Analysis of Single Cells

A Microfluidic Chip for the Versatile Chemical Analysis of Single Cells

Published on: October 15, 2013

Microprobe Capillary Electrophoresis Mass Spectrometry for Single-cell Metabolomics in Live Frog (Xenopus laevis) Embryos

Microprobe Capillary Electrophoresis Mass Spectrometry for Single-cell Metabolomics in Live Frog (Xenopus laevis) Embryos

Published on: December 22, 2017

Precise Electrochemical Sizing of Individual Electro-Inactive Particles

Precise Electrochemical Sizing of Individual Electro-Inactive Particles

Published on: August 4, 2023

Area of Science:

Electrochemistry
Cell Biology
Analytical Chemistry

Background:

Needle-type voltammetric ultramicroelectrodes possess high sensitivity and rapid response times.
Their micrometer-scale tip diameters are suitable for analyzing isolated living cells.
Accurate electrochemical measurements require gentle tip placement and precise distance control.

Purpose of the Study:

To explore the application of voltammetric ultramicroelectrodes in single-cell microelectrochemistry.
To review recent findings on fundamental cellular mechanisms investigated using these techniques.

Main Methods:

Utilizing needle-type voltammetric ultramicroelectrodes for electrochemical measurements.
Focusing on precise tip placement and distance control to minimize stress on cells.
Ensuring ultramicroelectrode selectivity for target species involved in cellular processes.

Main Results:

Demonstrated exceptional sensitivity for detecting redox-active substances.
Achieved rapid response times crucial for dynamic cellular analysis.
Highlighted the importance of accurate tip-to-cell distance for reliable data.

Conclusions:

Voltammetric ultramicroelectrodes are ideal for analyzing the chemical environment of living cells.
These techniques provide insights into cellular actions like growth, respiration, and uptake/release.
Recent results offer a deeper understanding of fundamental cell function mechanisms.