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An Ex Vivo Tissue Culture Model of Cartilage Remodeling in Bovine Knee Explants
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An Ex Vivo Tissue Culture Model of Cartilage Remodeling in Bovine Knee Explants

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Measurement of glycosaminoglycan release from cartilage explants

John S Mort, Peter J Roughley

    Methods in Molecular Medicine
    |October 24, 2007
    PubMed

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    Glycosaminoglycans01:23

    Glycosaminoglycans

    Glycosaminoglycans (GAGs), also known as mucopolysaccharides, are long and linear polymers comprising of specific repeating disaccharides - the amino sugar that can be N-acetylglucosamine or N-acetylgalactosamine, and a uronic acid that is usually glucuronic acid or iduronic acid.
    GAGS are found in the extracellular matrix of vertebrates, invertebrates, and bacteria. Due to their polar nature they attract water, and serve as excellent lubricants or shock absorbers in an animal body.
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