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Olfactory groove meningiomas: surgical technique and follow-up review
Benedicto Oscar Colli1, Carlos Gilberto Carlotti, João Alberto Assirati
1Division of Neurosurgery, Department of Surgery, Hospital das Clinicas, Ribeirão Preto Medical School, University of São Paulo, 14048-900 Ribeirão Preto, SP, Brazil. bocolli@fmrp.usp.br
Background:
Olfactory groove meningiomas comprise 4-10% of the intracranial meningiomas. Generally they give signs of brain compression due to great size they reach before diagnosis. In this study, the clinical outcome of patients with olfactory groove meningiomas surgically treated was analyzed.
Method:
17 patients operated on from 1988-2006. Female: 16, Male: 1. Age: 19-76 years-old (mean=53.12 +/- 13.11).
Follow-Up:
1-209 months (mean=51.07 +/- 12.73. Bifrontal/bifrontal-bi-orbital approaches were used. Outcome was analyzed using survival/recurrence-free Kaplan-Mayer curves.
Results:
16 had WHO grade 1; one grade 2 meningiomas. Resection Simpson's grade 1 was in achieved in 64.7%, grade 2 in 29.4% and grade 3 in 5.9%. There was no recurrence during the follow-up. Global and operative mortality were 11.8%. Main postoperative complications were osteomyelitis (11.8%) and pneumonia (5.9%).
Conclusion:
Extensive approaches allowed total resection of most olfactory groove meningiomas with no recurrence during the follow-up, but operative mortality and local complications were high.
Insights
Surgical treatment of olfactory groove meningiomas using extensive approaches achieved total resection with no recurrence. However, operative mortality and complication rates were high in this patient cohort.
Area of Science:
- Neurosurgery
- Oncology
Background:
- Olfactory groove meningiomas represent 4-10% of intracranial tumors.
- These tumors often present with symptoms of brain compression due to their large size at diagnosis.
Purpose of the Study:
- To analyze the clinical outcomes of patients surgically treated for olfactory groove meningiomas.
Main Methods:
- A retrospective analysis of 17 patients (16 female, 1 male; age 19-76) operated on between 1988 and 2006.
- Surgical approaches included bifrontal and bifrontal-bi-orbital techniques.
- Outcomes were assessed using Kaplan-Meier survival and recurrence-free curves.
Main Results:
- 16 tumors were WHO grade 1, and one was grade 2.
- Simpson's grade 1 resection was achieved in 64.7% of cases.
- No recurrence was observed during follow-up (mean 51.07 months).
- Global and operative mortality rates were 11.8%.
- Postoperative complications included osteomyelitis (11.8%) and pneumonia (5.9%).
Conclusions:
- Extensive surgical approaches facilitate complete resection of olfactory groove meningiomas, leading to no recurrence.
- High rates of operative mortality and local complications were noted.
