Related Experiment Video
Updated: Aug 15, 2026

Preparation of Stable Bicyclic Aziridinium Ions and Their Ring-Opening for the Synthesis of Azaheterocycles
Published on: August 22, 2018
Long-chain phenols from the bark of Amphypterygium adstringens
R Mata1, F Calzada, A Navarrete
1Departamento de Farmacia, Facultad de Química, Universidad Nacional Autónoma de México, D.F.
Abstract:
The hexane extract of the stem bark of Amphypterygium adstringens at a dose of 100 mg/kg subcutaneously exhibited significant hypocholesterolemic effect on 24-h fasted rats, lowering the cholesterol levels by 31%, an effect similar to 15 mg/kg estrone given by the same route. Column chromatography of the active extract allowed the isolation of two mixtures of long chain phenols (Mixture I and Mixture II). According to GC/MS analysis, Mixture I contained five alkyl phenolic acids and Mixture II three alkyl phenolic aldehydes. Neither of the mixtures exhibited significant hypocholesterolemic activity at doses up to 15 mg/kg subcutaneously.
Related Concept Videos
Aromatic Compounds: Overview
In 1825, Faraday isolated benzene...
ortho–para-Directing Activators: –CH3, –OH, –⁠NH2, –OCH3
Benzene to 1,4-Cyclohexadiene: Birch Reduction Mechanism
Radical Chain-Growth Polymerization: Overview
Olefin Metathesis Polymerization: Ring-Opening Metathesis Polymerization (ROMP)
π Electron Effects on Chemical Shift: Aromatic and Antiaromatic Compounds

