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Updated: Jul 10, 2026

A Scalable Balz-Schiemann Reaction Protocol in a Continuous Flow Reactor
Published on: February 10, 2023
Enhanced dibenzothiophene biodesulfurization in a microchannel reactor
Ken-Ichi Noda1, Tomonari Kogure, Shiro Irisa
1Department of Molecular Biotechnology, Hiroshima University, Higashi-Hiroshima, Hiroshima, Japan. noda@hiroshima-u.ac.jp
Abstract:
A microchannel reactor system was used in a biodesulfurization process in which the rate of biodesulfurization in the oil/water phase of the microchannel reaction was more than nine-fold that in a batch (control) reaction. In addition, the microchannel reaction system using a bacterial cell suspension degraded alkylated dibenzothiophene that was not degraded by the batch reaction system. This work provides a foundation for the application of a microchannel reactor system consisting of biological catalysts using an oil/water phase reaction.
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