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Related Experiment Video

Updated: Jul 10, 2026

Minimally Invasive Isolated Limb Perfusion (MI-ILP) for Locally Advanced Melanomas and Sarcomas of the Extremity
09:38

Minimally Invasive Isolated Limb Perfusion (MI-ILP) for Locally Advanced Melanomas and Sarcomas of the Extremity

Published on: January 31, 2025

Isolated limb infusion for melanoma.

Z Al-Hilli1, W Khan, A D K Hill

  • 1Department of Surgery, Royal College of Surgeons in Ireland, Beaumont Hospital, Ireland.

The Surgeon : Journal of the Royal Colleges of Surgeons of Edinburgh and Ireland
|October 26, 2007
PubMed
Summary

Isolated limb infusion delivers chemotherapy for unresectable, localized melanoma. This treatment offers symptom relief for extensive skin disease affecting a single limb.

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Area of Science:

  • Oncology
  • Surgical Oncology

Background:

  • Malignant melanoma can be confined to a single limb.
  • Extensive cutaneous disease may not be surgically resectable.

Purpose of the Study:

  • To describe the palliative role of isolated limb infusion (ILI) for unresectable malignant melanoma.

Main Methods:

  • Administration of cytotoxic drugs via isolated limb infusion.
  • Targeting limbs with malignant melanoma confined and not surgically resectable.

Main Results:

  • Isolated limb infusion provides palliation for extensive cutaneous disease.
  • Effective for patients with unresectable limb-confined melanoma.

Conclusions:

  • Isolated limb infusion is a palliative treatment option.
  • Suitable for extensive, unresectable malignant melanoma of the limb.

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Last Updated: Jul 10, 2026

Minimally Invasive Isolated Limb Perfusion (MI-ILP) for Locally Advanced Melanomas and Sarcomas of the Extremity
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Percutaneous Hepatic Perfusion (PHP) with Melphalan as a Treatment for Unresectable Metastases Confined to the Liver
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Percutaneous Hepatic Perfusion (PHP) with Melphalan as a Treatment for Unresectable Metastases Confined to the Liver

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