Development of a multi-channel system for intrinsic cardiac neural recording

Recent clinical evidence suggests that abnormal neural input can contribute to the onset perpetuation of atrial arrhythmias, such that neural elements have become potential targets for ablation. A better understanding of the influence of the cardiac autonomous nervous system is required to improve therapy. We have developed a multi-channel system to record neural activity simultaneously at different intra and pericardiac locations. The paper presents the specific requirements to be met for recording neuronal extracellular potentials in these repertoires of neurons and the solutions that were adopted.