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Updated: Jul 10, 2026

High Content Screening Analysis to Evaluate the Toxicological Effects of Harmful and Potentially Harmful Constituents (HPHC)
Published on: May 10, 2016
Require comprehensive safety data for all chemicals
Joseph H Guth1, Richard A Denison, Jennifer Sass
1Science & Environmental Health Network, 1050 Neilson St. Albany, CA 94706, USA. joe@sehn.org
Abstract:
Reform No. 5 of the Louisville Charter addresses the pervasive lack of publicly available information about the effects of many chemicals on human health and the environment. This lack of information persists for the majority of chemicals in commerce because the current laws in the United States do not systematically require it to be produced or motivate its voluntary production. These information gaps undermine the effectiveness of the existing environmental statutes, the liability system, the ability of the market to stimulate development of safer chemicals and, if they persist, complete realization of the other elements of the Louisville Charter. Therefore, this Reform calls for manufacturers of chemicals to be required to provide health and safety information as a condition for placing and keeping a chemical on the market.
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