Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Bipolar Disorder01:30

Bipolar Disorder

Bipolar disorder is a chronic mental health condition marked by significant mood fluctuations, including episodes of mania and depression. Elevated energy levels, heightened mood or irritability, impulsive behavior, reduced sleep needs, rapid speech, racing thoughts, inflated self-esteem, and distractibility characterize mania. Individuals with bipolar disorder often alternate between depressive and manic states, with periods of emotional stability lasting an average of six months to a year.
Socioemotional Experience and Gender Development01:30

Socioemotional Experience and Gender Development

Social-emotional experiences and cultural influences play significant roles in shaping gender development. During middle childhood, from ages 6 to 11, peer groups become dominant in reinforcing gender norms. Children in this age group often align with same-gender peer groups, which actively encourage behaviors that conform to traditional gender roles. For instance, boys may be discouraged from engaging in activities perceived as feminine, reinforcing culturally dictated norms about masculinity...
Panic Disorder01:27

Panic Disorder

Panic disorder is an anxiety disorder characterized by recurrent and sudden minutes-long episodes of intense fear, known as panic attacks. These attacks may feel like heart attacks and often happen without warning or a specific cause. They can include symptoms such as rapid heart rate, shortness of breath, chest pain, trembling, sweating, dizziness, and a sense of helplessness. During a panic attack, individuals may feel as though they are experiencing a heart attack or are in a...
Conduct Disorder01:28

Conduct Disorder

Conduct disorder is a complex mental health diagnosis characterized by a repetitive and persistent pattern of behavior that violates societal norms, the rights of others, or age-appropriate rules. The diagnostic criteria for conduct disorder require the presence of at least three problematic behaviors within the past 12 months, with at least one occurring in the past six months. These behaviors are grouped into four categories: aggression toward people and animals; destruction of property;...
Oppositional Defiant Disorder01:30

Oppositional Defiant Disorder

A persistent pattern of angry or irritable mood, defiant behavior, or vindictiveness characterizes Oppositional Defiant Disorder (ODD). Symptoms must occur over at least six months, involve interactions with individuals beyond siblings, and meet specific diagnostic criteria to be clinically significant. The disorder affects emotional regulation, social interactions, and behavior, often manifesting early in life and influencing long-term development and functioning.
Diagnostic Criteria and...
Sex Linked Disorders01:43

Sex Linked Disorders

Like autosomes, sex chromosomes contain a variety of genes necessary for normal body function. When a mutation in one of these genes results in biological deficits, the disorder is considered sex-linked.

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Identifying the Aggression Impulsive/Reactive (AIR) Profile in Youth With Behavioral Challenges.

JAACAP open·2026
Same author

Evaluating large language models for abstract evaluation tasks: an empirical study.

Frontiers in research metrics and analytics·2026
Same author

Measurement-Based Care Benchmarks and Bipolar Classification in ABCD Youth.

medRxiv : the preprint server for health sciences·2026
Same author

Long-Term Stability of IQ Scores for Children With Neurodevelopmental Disabilities: Stable Global IQ But Unstable Index, Subtest, and Profile IQ Scores.

Journal of autism and developmental disorders·2026
Same author

Construct Validity of IQ in the Presence of Scatter: A Measurement Invariance Approach.

Assessment·2026
Same author

Are Differences in Social Drive in Childhood and Adolescence Diagnosis Specific? A Multimeasurement Subtyping Approach.

JAACAP open·2026

Related Experiment Video

Updated: Jul 10, 2026

Developing a Rat Model for Bipolar Disorder
04:42

Developing a Rat Model for Bipolar Disorder

Published on: May 2, 2025

Sex differences in pediatric bipolar disorder.

Jeanne M Duax1, Eric A Youngstrom, Joseph R Calabrese

  • 1Department of Psychology, Case Western Reserve University, Cleveland, OH 44106-7123, USA. jeanne.duax@case.edu

The Journal of Clinical Psychiatry
|October 27, 2007
PubMed
Summary

Pediatric bipolar disorder shows no sex differences in diagnosis rates, but boys more often present with mania, while girls show higher rates of depression. Age impacts depression levels but not mania in children.

More Related Videos

Social Defeat Stress Model for Adolescent C57BL/6 Male and Female Mice
07:15

Social Defeat Stress Model for Adolescent C57BL/6 Male and Female Mice

Published on: March 15, 2024

Related Experiment Videos

Last Updated: Jul 10, 2026

Developing a Rat Model for Bipolar Disorder
04:42

Developing a Rat Model for Bipolar Disorder

Published on: May 2, 2025

Social Defeat Stress Model for Adolescent C57BL/6 Male and Female Mice
07:15

Social Defeat Stress Model for Adolescent C57BL/6 Male and Female Mice

Published on: March 15, 2024

Area of Science:

  • Child and Adolescent Psychiatry
  • Neurodevelopmental Disorders
  • Mood Disorders

Background:

  • Pediatric bipolar disorder (PBD) diagnosis and presentation can vary.
  • Understanding sex differences in PBD is crucial for accurate diagnosis and treatment.
  • Previous research indicates potential gender-related disparities in mood disorder symptomatology.

Purpose of the Study:

  • To investigate sex differences in pediatric bipolar disorder subtypes and symptom severity.
  • To explore how manic and depressive symptoms manifest differently in boys and girls with bipolar disorder.
  • To identify age-related patterns in mood symptomatology within pediatric bipolar disorder.

Main Methods:

  • Utilized data from 760 youth (aged 5-17) in an outpatient setting enriched for bipolar disorder.
  • Assessed DSM-IV diagnoses using the Schedule for Affective Disorders and Schizophrenia for School-Age Children-Epidemiologic Version.
  • Measured presenting mood states with the Young Mania Rating Scale and Children's Depression Rating Scale-Revised.

Main Results:

  • No significant sex differences were found in the rates of bipolar spectrum disorders or subtypes.
  • Boys were more likely to present with manic mood states, while girls showed higher rates of depressed mood.
  • Older children exhibited higher levels of depressed mood, with no age differences in manic mood severity.

Conclusions:

  • Bipolar disorder manifests differently in boys and girls despite similar diagnostic rates.
  • Clinicians must consider diverse mood state presentations for accurate pediatric bipolar disorder diagnosis and treatment.
  • Further research is needed on genetic, pubertal, cognitive, and environmental influences on sex-specific PBD symptom expression.