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Updated: Jul 10, 2026

08:05
Occlusion of the Great and Small Saphenous Vein Using Copolymeric Glue Based on N-Butyl Cyanoacrylate and Methacryloxy Sulfolane
Published on: December 9, 2022
[Saphenous graft angioplasty]
H Benamer1, V Stratiev, P Schiano
1Service de cardiologie, hôpital Foch, 40, rue Worth, 92150 Suresnes, France. hbenamer@club-internet.fr
Summary
Saphenous graft angioplasty is complex and carries risks. Protection devices improve outcomes, while drug-eluting stents show promise but aren't yet standard practice.
Area of Science:
- Interventional Cardiology
- Vascular Surgery
Background:
- Saphenous graft angioplasty is performed in less than 5% of cases.
- This procedure is complex, particularly in fragile patients, with a higher complication rate.
Observation:
- Key challenges include extensive graft lesions, risk of distal embolism, slow-flow phenomenon, and high restenosis rates.
- Glycoprotein IIb/IIIa inhibitors have shown limited efficacy.
Findings:
- Protection devices are effective and recommended when technically feasible.
- Bare-metal stents are associated with very high restenosis rates in saphenous grafts.
- Drug-eluting stents demonstrate encouraging results but are not yet approved for this indication.
Implications:
- Technical refinements and appropriate device selection are crucial for successful saphenous graft angioplasty.
- Further research and regulatory approval are needed for wider adoption of drug-eluting stents in this setting.
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