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Updated: Jul 10, 2026

An Immunohistopathologic Study to Profile the Folate Receptor Beta Macrophage and Vascular Immune Microenvironment in Giant Cell Arteritis
Published on: February 8, 2019
Ruptured vertebrobasilar aneurysm associated with giant cell arteritis in a young boy
Seth Love1, Shelley Renowden, Michael Carter
1Department of Neuropathology, Institute of Clinical Neurosciences, Frenchay Hospital, Bristol BS16 1LE, UK. seth.love@bris.ac.uk
Abstract:
Intracranial aneurysms are rare in early childhood and there is little published information on their histology. We report a young boy who died of subarachnoid haemorrhage, 29 months after coiling of a giant vertebrobasilar aneurysm. Histology of the aneurysm revealed intramural inflammation with giant cells and fragmentation of the internal elastic lamina. The findings highlight the need for detailed examination in such cases, to elucidate the pathogenesis and pathology of cerebrovascular aneurysms in this age group.
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