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Related Concept Videos

Homeostatic Imbalance01:10

Homeostatic Imbalance

Homeostasis is the maintenance of a stable internal environment within the body, which is crucial for the proper functioning of cells, tissues, organs, and organ systems. The body has various control mechanisms that work together to regulate various physiological parameters such as temperature, blood pressure, pH balance, and fluid balance, to name a few. These control mechanisms are based on feedback loops that can be either positive or negative.
However, sometimes these feedback loops fail,...
Decision Making01:20

Decision Making

Decision-making is a fundamental cognitive process that involves evaluating alternatives and selecting among them. This process can range from simple choices, such as deciding what to wear, to complex decisions, like choosing a major in college or a career path. The complexity of the decision often dictates the approach we use, which can be broadly categorized into two types: automatic and controlled decision-making.
Automatic decision-making is fast, intuitive, and relies on gut feelings...
Psychosis: Pathophysiology of Schizophrenia and Other Psychotic Disorders01:27

Psychosis: Pathophysiology of Schizophrenia and Other Psychotic Disorders

Schizophrenia is a neurodevelopmental disorder whose origins are rooted in complex genetic components. Despite our burgeoning understanding, the pathophysiology of this disorder remains incompletely deciphered.
Researchers have identified genetic factors that increase susceptibility to schizophrenia, underscoring the intricate interplay between genetics and environment in disease development. At the core of schizophrenia's pathophysiology is excessive dopaminergic neurotransmission within the...
Introduction to Psychological Disorders01:19

Introduction to Psychological Disorders

Abnormal behavior, often referred to as mental illness, results from changes in brain function that influence thought patterns, behaviors, and social interactions. Psychologists and psychiatrists typically assess abnormal behavior using three primary criteria: deviance, maladaptation, and personal distress, particularly when these traits persist over long periods.
Deviant Behavior
Deviance in behavior refers to actions or thought patterns that significantly diverge from societal norms or...
Hypothalamic-Pituitary Axis01:37

Hypothalamic-Pituitary Axis

The response to stress—be it physical or psychological, acute or chronic—involves activation of the Hypothalamic-Pituitary-Adrenal (HPA) axis. The HPA axis is part of the neuroendocrine system because it involves both neuronal and hormonal communication. Its function is to regulate homeostatic systems—metabolic, cardiovascular, and immune—providing the necessary means to respond to a stressor.
Disorders of the Nervous Tissue01:28

Disorders of the Nervous Tissue

Nervous tissue is a vital component of the human body's communication system, enabling us to perceive and respond to stimuli. However, like all other tissues, it is vulnerable to disorders and diseases that can significantly impact our neurological functioning.
Homeostatic Imbalances:
Alzheimer's disease manifests as a gradual decline in memory and cognitive abilities, attributed to the buildup of amyloid plaques and neurofibrillary tangles in the brain.
Parkinson's disease arises from the...

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Related Experiment Video

Updated: Jul 10, 2026

The Adventures of Fundi Intervention Based on the Cognitive and Emotional Processing in Attention Deficit Hyperactive Disorder Patients
05:48

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Published on: June 12, 2020

Decision-making dysfunctions in psychiatry--altered homeostatic processing?

Martin P Paulus1

  • 1Department of Psychiatry, University of California at San Diego, 8950 Villa La Jolla Drive, La Jolla, CA 92037-0985, USA. mpaulus@ucsd.edu

Science (New York, N.Y.)
|October 27, 2007
PubMed
Summary

Decision-making, a homeostatic process, is altered in psychiatric disorders. Dysfunctional choices may stem from core homeostatic regulation issues, impacting outcomes and context adaptation.

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Area of Science:

  • Neuroscience
  • Psychiatry
  • Decision Science

Background:

  • Decision-making involves selecting actions with outcomes that alter the decision-maker's state.
  • This process is integral to maintaining homeostasis.
  • Psychiatric disorders are characterized by altered decision-making patterns, often selecting non-optimal or non-homeostatic options.

Purpose of the Study:

  • To explore the fundamental relationship between homeostatic regulation problems and dysfunctional decision-making in psychiatric disorders.
  • To investigate specific manifestations of altered decision-making related to temporal factors, feedback integration, contextual adaptation, and maladaptive responses.

Main Methods:

  • The study likely involved analyzing decision-making behaviors in individuals with psychiatric disorders.
  • Methods may include computational modeling, behavioral experiments, and analysis of temporal dynamics, feedback processing, and strategy adaptation.

Main Results:

  • Individuals with psychiatric disorders exhibit non-optimal and non-homeostatic decision-making.
  • These patterns may be linked to underlying deficits in homeostatic regulation.
  • Manifestations include altered sensitivity to decision-outcome timing, feedback integration, and context-dependent strategy adjustments.

Conclusions:

  • Dysfunctional decision-making in psychiatric disorders is fundamentally tied to problems in homeostatic regulation.
  • Understanding these links can illuminate the neurobiological basis of psychiatric conditions.
  • Targeting homeostatic dysregulation may offer novel therapeutic strategies for improving decision-making deficits.