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Related Experiment Videos

The Molecule Pages database.

Brian Saunders1, Stephen Lyon, Matthew Day

  • 1San Diego Supercomputer Center San Diego, La Jolla, CA 92093, Nature Publishing Group, 25 First Street, Cambridge, MA 02141, USA.

Nucleic Acids Research
|October 30, 2007
PubMed
Summary
This summary is machine-generated.

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The UCSD-Nature Signaling Gateway provides expert-authored, peer-reviewed data on over 3800 mammalian proteins involved in cellular signaling. This accessible resource aids researchers in understanding complex biological pathways.

Area of Science:

  • Biochemistry
  • Molecular Biology
  • Bioinformatics

Background:

  • Cellular signaling pathways are crucial for biological processes.
  • A comprehensive, reliable resource for mammalian signaling proteins is needed.
  • Existing data sources may lack expert curation and structured bioinformatics data.

Purpose of the Study:

  • To present the UCSD-Nature Signaling Gateway Molecule Pages as a valuable resource for the scientific community.
  • To highlight the expert-authored and peer-reviewed nature of the data.
  • To emphasize the accessibility and utility of the structured data for research.

Main Methods:

  • Compilation of expert-authored reviews and structured data on over 3800 mammalian signaling proteins.
  • Integration of published literature, public data sources, and sequence analysis.

Related Experiment Videos

  • Development of an object-relational database with a web-based presentation layer.
  • Anonymous peer review by the Nature Publishing Group.

    • Main Results:

    • The Signaling Gateway Molecule Pages offer detailed information on mammalian signaling proteins.
    • Data includes full-text reviews, protein interactions, states, transitions, and functions.
    • The resource is freely accessible and utilizes a multi-tier architecture.
    • The platform is routinely accessed by a large research community.

    Conclusions:

    • The UCSD-Nature Signaling Gateway is a robust, expertly curated resource for mammalian cell signaling research.
    • Its structured data and accessibility facilitate bioinformatics interrogation and scientific discovery.
    • The platform serves as a vital tool for a broad research community.