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Updated: Jul 10, 2026

Computer-Aided Three-Dimensional Visualization in the Treatment of Locally Advanced Thyroid Cancer
Published on: June 9, 2023
Radioactive iodine therapy in poorly differentiated thyroid cancer
R Michael Tuttle1, Ravinder K Grewal, Steve M Larson
1Department of Radiology, Memorial Hospital, Weill Medical College of Cornell University New York, NY, USA. tuttlem@mskcc.org
Background:
A 55-year-old male was diagnosed with poorly differentiated thyroid cancer after total thyroidectomy, which was performed because of progressive enlargement of a dominant thyroid nodule. He developed an early cervical recurrence that was treated with modified neck dissection. He subsequently developed biopsy-proven progressive pulmonary metastases.
Investigations:
Neck and chest CT scans, laboratory tests, CT-guided fine-needle aspiration biopsy, [18F]-2-fluoro-2-deoxy-D-glucose-PET scan, lesional dosimetry using 124I PET scan, diagnostic radioactive iodine (RAI) scanning, whole-body and blood RAI dosimetry, and single-photon-emission CT.
Diagnosis:
Stage IV poorly differentiated thyroid cancer.
Management:
Surgical resection of cervical recurrence, RAI therapy.
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