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Analysis of 18FDG PET/CT Imaging as a Tool for Studying Mycobacterium tuberculosis Infection and Treatment in Non-human Primates
Published on: September 5, 2017
[Tuberculosis in the Czech Republic during 2006]
J Homolka1, F Krejbich, J Holub
1I. klinika tuberkulózy a respiracních nemocí 1. LF UK a VFN, Praha. jhomolka@cesnet.cz
Casopis Lekaru Ceskych
|October 31, 2007
Summary
Tuberculosis cases declined in the Czech Republic in 2006, with low drug resistance. Future efforts should focus on active case-finding in high-risk groups to further reduce tuberculosis incidence.
Area of Science:
- Public Health
- Epidemiology
- Infectious Disease Control
Context:
- The Czech Republic observed a continued decrease in tuberculosis notification rates in 2006.
- 973 cases (9.5/100,000) of all tuberculosis types were reported, including 799 pulmonary cases.
- A significant portion of pulmonary tuberculosis cases (5.5/100,000) were definite pulmonary tuberculosis.
Purpose:
- To analyze the trends in tuberculosis notification rates and drug resistance in the Czech Republic.
- To evaluate the effectiveness of passive versus active case-finding strategies for tuberculosis detection.
- To identify future targets for tuberculosis control, including active case-finding and latent infection monitoring.
Summary:
- Tuberculosis notification rates continued to decline in the Czech Republic in 2006.
- Drug resistance was low at 7.4%, with multidrug-resistant tuberculosis (MDR-TB) at 1.4% of confirmed cases.
- Passive case-finding diagnosed the majority of tuberculosis cases (74.7%), while active case-finding identified only 11.7%.
Impact:
- The low drug resistance and effective treatment suggest a presumption of further decline in tuberculosis.
- There is a need to increase active case-finding in high-risk populations to improve tuberculosis detection rates.
- Monitoring latent tuberculosis infection is a key future strategy for comprehensive tuberculosis control.
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