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Updated: Jul 10, 2026

Preparation and Characterization of Individual and Multi-drug Loaded Physically Entrapped Polymeric Micelles
Published on: August 28, 2015
[Influencing factors on dampproof effect of microcapsules and study on mechanism]
1Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China. fyi@vip.sina.com
Objective:
The influence of spray drying technology on the damp proof effect of microcapsules and the mechanism were studied.
Method:
The microcapsules prepared with different spray drying parameters have been put in certain surroundings for 12 hours, then the hygroscopic curves were gotten; the mechanism was studied from the following aspects: solvent residue, film's shrink and particle size.
Result:
The damp proof effect enhanced with the increase of inlet air temperature and the decrease of flow rate and air pressure. The properties of the wall, the solvent residue and particle size can influence the damp proof effect of the microcapsules.
Conclusion:
The physical properties of microcapsules are different because of the different spray drying parameters, which lead to different damp proof effect of microcapsules.
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