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Evaluation of two different potency tests for leptospirosis vaccine vax-SPIRAL
Juan Francisco Núñez1, Ester María Fajardo, Elizabeth Pérez
1Instituto Finlay, Ciudad de La Habana, Cuba. jnunez@finlay.edu.cu
Revista Cubana De Medicina Tropical
|October 31, 2007
Abstract:
Two different potency tests were evaluated, consisting in one-dilution used to determine 50% lethal dose (LD50) and four--dilution used to calculate 50% effective dose (ED50), respectively. Our experience has led to propose the four-dilution test for routine lot releasing.
