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Related Concept Videos

Pharmacokinetics in Pediatric Patients: Drug Excretion01:26

Pharmacokinetics in Pediatric Patients: Drug Excretion

In pediatric medicine, understanding the renal function and drug elimination nuances is crucial for administering safe and effective treatments. Newborns, in particular, display markedly slower renal functions than adults, profoundly affecting how drugs are cleared from their bodies. This slower drug clearance requires clinicians to extend the dosing intervals for many medications to prevent drug accumulation and toxicity while ensuring therapeutic efficacy.One key area where these adjustments...
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Epistaxis

Epistaxis, or nosebleeds, occurs when small, swollen blood vessels in the nasal mucous membrane rupture. Typically, the anterior septum is the primary site of occurrence.
Etiology
Possible causes of this condition include high blood pressure, trauma, low humidity, upper respiratory tract infections, allergies, foreign bodies, nasal inhalation of corticosteroids or illicit drugs, excessive use of decongestant nasal sprays, facial or nasal surgery, anatomic malformation, tumors, or systemic...
Prevention of Further Absorption of Poison01:14

Prevention of Further Absorption of Poison

In cases of acute poisoning, the primary objective is to prevent further absorption of the toxic substance into the body. Immediate interventions using various decontamination techniques targeting the gastrointestinal (GI) tract can achieve this. Decontamination is crucial to prevent poison from entering the systemic circulation, which involves washing affected areas with water and mild soap and removing contaminated clothing. Once external decontamination is done, attention must be turned to...
Pharmacokinetics in Pediatric Patients: Drug Distribution01:17

Pharmacokinetics in Pediatric Patients: Drug Distribution

Drug distribution in the pediatric population exhibits unique challenges and considerations due to the physiological differences between children, particularly neonates and infants, and adults. A crucial aspect of pediatric pharmacology is understanding how these differences impact the pharmacokinetics of various drugs, necessitating age-specific dosing strategies to ensure efficacy and safety.Neonates and infants have a higher total body water content, ~75%–90% of their body weight, compared...
Drug Dosing: Infants and Children01:29

Drug Dosing: Infants and Children

Pediatric patient dosages diverge from adults due to disparities in body surface area, total body water, and extracellular fluid per kilogram of body weight. The dosing regimen considers the variations in pharmacokinetics and pharmacology across distinct age groups, encompassing preterm newborns, infants, young children, older children, and adolescents. Calculation of pediatric patient doses is predicated on determining body surface area, which exhibits a superior correlation with the child's...
Local Anesthetics: Clinical Application as Epidural Anesthesia01:29

Local Anesthetics: Clinical Application as Epidural Anesthesia

Epidural anesthetics are administered in the fat-filled epidural space, the outermost part of the spinal canal. This technique is commonly employed for pain management and anesthesia during lower abdomen and pelvis surgeries or labor and delivery.
Since epidural anesthetics can be infused through an epidural catheter, all types of drugs, including short-acting ones, can be administered. Chloroprocaine and lidocaine are examples of short and long-duration anesthetics, respectively. Bupivacaine...

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Related Experiment Video

Updated: Jul 10, 2026

A Neonatal Rodent Model of Retroorbital Vein Injection
04:39

A Neonatal Rodent Model of Retroorbital Vein Injection

Published on: February 23, 2024

Preventing extravasation injuries in neonates.

Rachael Tong1

  • 1Royal Hospital of Sick Children, Glasgow.

Paediatric Nursing
|November 1, 2007
PubMed
Summary

Preventing extravasation injuries in vulnerable neonates requires vigilant intravenous access monitoring. Addressing barriers like staffing and training can improve nursing care and reduce these harmful events.

Area of Science:

  • Neonatal intensive care
  • Vascular access nursing
  • Patient safety

Background:

  • Sick and preterm neonates are highly susceptible to extravasation injuries.
  • Current monitoring practices for intravenous access sites in neonatal units face significant barriers.
  • Extravasation injuries can have severe consequences for vulnerable infants.

Purpose of the Study:

  • To identify barriers to rigorous and continuous monitoring of intravenous access sites in neonatal units.
  • To explore themes supporting quality nursing practice in preventing extravasation injuries.
  • To provide recommendations for reducing the incidence of extravasation injury in neonates.

Main Methods:

  • Literature review to identify themes related to quality nursing practice.

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Last Updated: Jul 10, 2026

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  • Analysis of identified themes including staffing, skill mix, preceptorship, professional development, record keeping, and communication.
  • Exploration of how these themes impact the prevention of extravasation injuries.
  • Main Results:

    • Key themes influencing nursing practice in intravenous access monitoring were identified.
    • Staffing levels, staff training (preceptorship and professional development), and effective communication are critical.
    • Improved record keeping is essential for continuous monitoring and patient safety.

    Conclusions:

    • A 'hyper-vigilant' approach to monitoring intravenous access is crucial for preventing extravasation injuries in neonates.
    • Addressing identified barriers through strategic improvements in nursing practice is recommended.
    • Implementing these recommendations can significantly reduce the incidence of extravasation injury in neonatal populations.