Highly conserved sequences mediate the dynamic interplay of basic helix-loop-helix proteins regulating retinogenesis.

Julio Hernandez1, Lidia Matter-Sadzinski, Dorota Skowronska-Krawczyk

  • 1Department of Biochemistry, Sciences II and Department of Ophthalmology, School of Medicine, University of Geneva, 1211, Genève 4, Switzerland.

Summary

The atonal homolog 5 (ATH5) protein controls retinal ganglion cell development. Three E-boxes on the ATH5 promoter are crucial for regulating gene expression during different stages of retina development.

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