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Updated: Jul 10, 2026

12:15
Generation of Monoclonal Antibodies Against Natural Products
Published on: April 6, 2019
Synthesis and natural distribution of anti-inflammatory alkamides from Echinacea
George A Kraus1, Jaehoon Bae, Lankun Wu
1Iowa State University, Department of Chemistry, Ames, IA 50011, USA. gakraus@iastate.edu
Molecules (Basel, Switzerland)
|November 1, 2007
Abstract:
The synthesis of the alkamides 2Z,4E-undeca-2,4-dien-8,10-diynoic acid isobutyl amide (1) and 2Z,4E-undeca-2,4-dien-8,10-diynoic acid isobutyl amide (5) was accomplished by organometallic coupling followed by introduction of the doubly unsaturated amide moiety. The distribution of these two amides in accessions of the nine species of Echinacea was determined.
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