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Related Concept Videos

Skin Cancer01:30

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Glaucoma: Overview01:25

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
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The Retinoblastoma Gene01:20

The Retinoblastoma Gene

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The Retinoblastoma Gene

Tumor suppressor genes are normal genes that can slow down cell division, repair DNA mistakes, or program the cells for apoptosis in case of irreparable damage. Hence, they play an essential role in preventing the proliferation of damaged cells.
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Related Experiment Video

Updated: Jul 10, 2026

Implantation and Evaluation of Melanoma in the Murine Choroid via Optical Coherence Tomography
05:46

Implantation and Evaluation of Melanoma in the Murine Choroid via Optical Coherence Tomography

Published on: December 2, 2022

Conjunctival nevus and melanoma.

A Furdova1, K Pesko, P Strmen

  • 1Department of Ophthalmology, Comenius University, Faculty of Medicine, Bratislava, Slovakia. afrf@mail.t-com.sk

Bratislavske Lekarske Listy
|November 2, 2007
PubMed
Summary

Conjunctival nevi are common benign eye tumors. This study tracked 70 patients, analyzing changes in pigmented conjunctival lesions to understand their progression and inform early detection of rare melanomas.

Area of Science:

  • Ophthalmology
  • Oncology
  • Dermatology

Background:

  • Conjunctival nevi are frequent benign ocular surface tumors.
  • Conjunctival melanomas are rare, potentially arising from nevi or primary acquired melanosis (PAM).
  • Early recognition of precursor lesions is crucial for managing pigmented conjunctival lesions.

Purpose of the Study:

  • To determine the frequency of size and pigmentation changes in benign conjunctival pigmented lesions.
  • To analyze the clinical course of epibulbar pigmented lesions.
  • To contribute to the understanding of conjunctival tumors and their management.

Main Methods:

  • Retrospective analysis of 70 patients with conjunctival pigmented lesions.
  • Study period: 1996-2006.

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  • Data collected at the Department of Ophthalmology, Faculty of Medicine, Comenius University, Bratislava.

    • Main Results:

    • The study focused on changes in size and pigmentation of benign conjunctival lesions.
    • Information on the progression of these lesions was gathered.
    • The study highlights the rarity of melanomas and the importance of monitoring benign lesions.

    Conclusions:

    • Surgical excision is generally effective for benign conjunctival lesions.
    • Advanced conjunctival melanomas may require aggressive treatment including radiotherapy or exenteration.
    • Management strategies vary based on lesion type and stage, from observation to systemic therapy.