Related Experiment Video
Updated: Jul 10, 2026

Midface Hypoplasia and Cranial Base Morphology in Syndromic Craniosynostosis: A Comparative Analysis Study Using a Predictive Regression Model
Published on: November 4, 2025
Changes in cranial base morphology in different malocclusions
1Department of Orthodontics, Faculty of Dentistry, Baskent University, Ankara, Turkey. omurorto@yahoo.com
Objectives:
To evaluate the differences in cranial base flexure between skeletal and dental Class I, Class II and Class III malocclusions.
Design:
Lateral cephalometric radiographs, matched for age, of skeletal Class I, Class II and Class III patients with an average vertical growth pattern were analyzed and compared.
Setting And Sample Population:
A total of 75 patients having skeletal Class I (n = 25), Class II (n = 25) and Class III (n = 25) malocclusions of Baskent University.
Experimental Variable:
Anterior (SN) and posterior (SBa) cranial base lengths, cranial base angle (N-S-Ba, N-S-Ar) and both anterior (SN-FH) and posterior (SBa-FH) cranial base inclinations were measured on the pretreatment lateral cephalograms.
Outcome Measure:
Size and shape differences in cranial base between different malocclusions.
Results:
Anterior and posterior cranial base lengths, and cranial base angles did not show statistically significant differences between the three groups studied. Both anterior and posterior cranial base inclinations were increased significantly in the Class III group compared with Class I and Class II groups.
Conclusions:
No differences were observed in anterior and posterior cranial base lengths, and cranial base angles between the three malocclusions. However, cranial base inclinations were increased in Class III malocclusions.
Related Concept Videos
Cranial Bones: Lateral View
The temporal bone forms the lower lateral side of the skull. The temporal bone is subdivided into several regions. The flattened upper portion is the squamous portion of the temporal bone. Below this area and projecting anteriorly is the zygomatic process of the temporal bone, which forms the posterior portion of the zygomatic arch. Posteriorly is the mastoid portion of the temporal bone. Projecting...
Cranial Bones: Superior and Posterior View
The frontal bone is the single bone that forms the forehead. At its anterior midline, between the eyebrows, there is a slight depression called the glabella. The frontal bone also forms the supraorbital margin of the orbit. Near the middle of this margin is the supraorbital foramen, the opening that provides passage for a sensory nerve to the forehead. The frontal bone is thickened just above each supraorbital margin,...
Overview of the Skull
The cranial vault surrounds and protects the brain and houses the middle and inner ear structures. This cavity is bounded superiorly by the rounded top of the skull, which...
Sutures of the Skull
Sutures are immobile joints between adjacent bones of the skull. The narrow gap between the bones is filled with dense, fibrous connective tissue that unites the bones. The long sutures located between the skull bones are not straight but instead follow irregular, tightly twisting paths. These twisting lines tightly...
Bone Formation by Intramembranous Ossification
The process begins when mesenchymal cells in the embryonic skeleton gather together and differentiate into osteogenic cells, which then develop into...
