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Updated: Jul 10, 2026

A 3D Organotypic Melanoma Spheroid Skin Model
Published on: May 18, 2018
Spontaneous regression of recurrent and metastatic Merkel cell carcinoma
Hidemichi Kubo1, Shigeto Matsushita, Tomoko Fukushige
1Department of Dermatology, Field of Sensory Organology, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan. lupin28@m3.kufm.kagoshima-u.ac.jp
Abstract:
Merkel cell carcinoma (MCC) is a malignant neuroendocrine tumor with a high rate of recurrence and metastasis. Despite its high degree of malignancy, spontaneous regression has been documented. We report an 87-year-old woman who presented with recurrent MCC on her left cheek and regional lymph node metastasis. Although she received no treatment due to her poor condition, the recurrent metastatic lesion regressed spontaneously within 2 months.
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