Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Cellular Adaptation IV: Dysplasia and Metaplasia01:24

Cellular Adaptation IV: Dysplasia and Metaplasia

DysplasiaDysplasia refers to abnormal changes in the size, shape, and organization of mature cells, characterized by pleomorphism, nuclear abnormalities, and increased mitotic activity. It commonly affects epithelial tissues, including the cervix, gastrointestinal tract, respiratory mucosa, and endometrium. Although it may occur alongside hyperplasia, dysplasia is not a true adaptive response but a preneoplastic change with potential to progress to cancer.When confined above the basement...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

From Presumed Leiomyoma to Stump: Laparoendoscopic Single-Site Hysterectomy with Contained Morcellation for a Large Unsuspected Borderline Smooth Muscle Tumor.

Diagnostics (Basel, Switzerland)·2026
Same author

Recurrent Distant Metastatic Endometrial Cancer Treated with Immunotherapy with Pembrolizumab: A Case Report and Literature Review.

Diagnostics (Basel, Switzerland)·2026
Same author

Prognostic factors and survival of patients with endometrial cancer: A 10-year retrospective cohort study in a tertiary referral center in Northern Taiwan.

Tzu chi medical journal·2026
Same author

Signaling Pathway Dissection After Progesterone Receptor Enhancement in an Immortalized Pre-Cancer Fallopian Tube Epithelial Cell Line.

International journal of molecular sciences·2026
Same author

Effects of extracorporeal shockwave therapy on pain and pelvic floor function in women with pelvic floor myofascial pain: a retrospective cohort analysis.

BMC women's health·2026
Same author

Impact of different prophylactic antibiotics regimens on the risk of urinary tract infections after hysterectomies due to benign Indications: A retrospective cohort study.

European journal of obstetrics, gynecology, and reproductive biology·2026

Related Experiment Video

Updated: Jul 10, 2026

RNAscope for In situ Detection of Transcriptionally Active Human Papillomavirus in Head and Neck Squamous Cell Carcinoma
10:26

RNAscope for In situ Detection of Transcriptionally Active Human Papillomavirus in Head and Neck Squamous Cell Carcinoma

Published on: March 11, 2014

Pap smears with reactive cellular changes: a prospective study.

Dah-Ching Ding1, Senzan Hsu, Sidney S Chen

  • 1Department of Obstetrics and Gynecology, Buddhist Tzu Chi General Hospital, and Graduate Institute of Medical Science, School of Medicine, Tzu Chi University, Hualien, Taiwan, ROC. dah1003@yahoo.com.tw

The Journal of Reproductive Medicine
|November 6, 2007
PubMed
Summary
This summary is machine-generated.

A study found that 30% of women with atypical squamous cells (ASCs) had cervical dysplasia and 6% had cervical cancer. Colposcopy and biopsy are recommended for women with ASCs.

More Related Videos

Four-color Fluorescence Immunohistochemistry of T-cell Subpopulations in Archival Formalin-fixed, Paraffin-embedded Human Oropharyngeal Squamous Cell Carcinoma Samples
07:43

Four-color Fluorescence Immunohistochemistry of T-cell Subpopulations in Archival Formalin-fixed, Paraffin-embedded Human Oropharyngeal Squamous Cell Carcinoma Samples

Published on: July 29, 2017

Related Experiment Videos

Last Updated: Jul 10, 2026

RNAscope for In situ Detection of Transcriptionally Active Human Papillomavirus in Head and Neck Squamous Cell Carcinoma
10:26

RNAscope for In situ Detection of Transcriptionally Active Human Papillomavirus in Head and Neck Squamous Cell Carcinoma

Published on: March 11, 2014

Four-color Fluorescence Immunohistochemistry of T-cell Subpopulations in Archival Formalin-fixed, Paraffin-embedded Human Oropharyngeal Squamous Cell Carcinoma Samples
07:43

Four-color Fluorescence Immunohistochemistry of T-cell Subpopulations in Archival Formalin-fixed, Paraffin-embedded Human Oropharyngeal Squamous Cell Carcinoma Samples

Published on: July 29, 2017

Area of Science:

  • Gynecology
  • Oncology
  • Pathology

Background:

  • Atypical squamous cells (ASCs) on Pap smears require further investigation.
  • Cervical dysplasia and cancer are significant health concerns for women.

Purpose of the Study:

  • To determine the prevalence of cervical dysplasia and cervical cancer in women diagnosed with ASCs.
  • To evaluate the necessity of colposcopy and biopsy in managing ASCs.

Main Methods:

  • Prospective study involving 49 women with ASCs from Pap smears.
  • All participants underwent colposcopy, biopsy, and endocervical curettage (ECC).
  • Pathological review of all specimens.

Main Results:

  • Histological examination revealed normal findings in 61% of cases.
  • Cervical dysplasia was identified in 18.3% (mild), 2% (moderate), and 4% (severe).
  • Squamous cell carcinoma was found in 4% and adenocarcinoma in 2% of cases.

Conclusions:

  • ASCs are associated with a 30% prevalence of cervical dysplasia and a 6% prevalence of cervical cancer.
  • Colposcopically directed biopsy and ECC are crucial for accurate diagnosis in women with ASCs.