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Microelectrode Guided Implantation of Electrodes into the Subthalamic Nucleus of Rats for Long-term Deep Brain Stimulation
Published on: October 2, 2015
Brain shift: an error factor during implantation of deep brain stimulation electrodes
Yasushi Miyagi1, Fumio Shima, Tomio Sasaki
1Division of Digital Patient, Digital Medicine Initiative, Kyushu University, Fukuoka, Japan. yamiyagi@digital.med.kyushu-u.ac.jp
Journal of Neurosurgery
|November 6, 2007
Summary
Brain shift during deep brain stimulation (DBS) surgery causes electrode misplacement. Unilateral procedures shift the brain contralaterally, while bilateral procedures cause a posterior shift, impacting accuracy.
Area of Science:
- Neurosurgery
- Neurology
- Medical Imaging
Background:
- Stereotactic neurosurgery requires precise electrode placement.
- Brain shift can significantly affect the accuracy of deep brain stimulation (DBS) electrode implantation.
Purpose of the Study:
- To investigate brain shift during unilateral and bilateral DBS electrode implantation.
- To analyze the impact of brain shift on electrode positioning.
Main Methods:
- Magnetic resonance (MR) imaging-guided and microelectrode-guided DBS electrode implantation in 18 patients.
- Assessment of brain shift by measuring changes in anterior and posterior commissures (AC and PC) coordinates.
- Comparison of virtual electrode positions (intraoperative X-ray) with actual positions (postoperative MR imaging).
Main Results:
- Unilateral DBS procedures resulted in a contralateral shift of the AC and PC.
- Bilateral DBS procedures led to a posterior (caudal) shift of the AC and PC.
- Brain shift is influenced by air invasion and loss of hemispheric support during sequential procedures.
Conclusions:
- Understanding brain shift tendencies is crucial for accurate stereotactic neurosurgery.
- Accurate electrode placement is vital for predicting therapeutic and adverse effects in DBS.
- Accounting for brain shift improves the precision of deep brain stimulation and other stereotactic interventions.
