[Two ways of constructing concealed penis model in rats: a comparative and analytical study]

Area of Science:

• Urology
• Animal Models
• Surgical Research

Background:

• Concealed penis, a condition affecting penile development, requires reliable experimental models for study.
• Understanding the impact of concealed penis on the corpus cavernosum is crucial for developing effective treatments.

Purpose of the Study:

• To establish a stable and reproducible rat experimental model of concealed penis.
• To investigate the effects of concealed penis on the structure and function of the corpus cavernosum.

Main Methods:

• Ninety male Sprague Dawley rats were divided into three groups: intra-purse suture (Group A), folding prepuce suture (Group B), and sham controls (Group C).
• Surgical techniques were employed to induce concealed penis in Groups A and B.
• Success rates and complications were meticulously recorded.

Main Results:

• Group A had a 36.7% success rate, with complications including post-operative urine retention and tissue ulceration.
• Group B achieved a 56.7% success rate, with fewer complications compared to Group A.
• Penile protrusion occurred in some rats during development and erection in both surgical groups.

Conclusions:

• Both surgical methods can successfully establish a stable rat model of concealed penis.
• The developed model mimics the natural course of concealed penis in humans.
• This model provides a valuable tool for further research into concealed penis and its effects on penile health.