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Assays for the Specific Growth Rate and Cell-binding Ability of Rotavirus
Published on: January 28, 2019
[Rotavirus infections in a paediatric hospital during 5 years]
C Doit1, P Mariani-Kurkdjian, A Bourrillon
1Service de microbiologie, hôpital Robert-Debré, 48, boulevard Sérurier, 75019 Paris, France. catherine.doit@rdb.aphp.fr
Insights
Rotavirus gastroenteritis frequently affects young children, often leading to hospital-acquired infections. This study highlights seasonal peaks and the significant burden of rotavirus in pediatric hospital settings.
Area of Science:
- Pediatric Infectious Diseases
- Gastroenterology
- Epidemiology
Context:
- Rotavirus is a leading cause of gastroenteritis in children globally.
- Hospital-acquired infections pose a significant challenge in pediatric units.
- Understanding local epidemiology is crucial for infection control.
Purpose:
- To investigate the epidemiology of gastroenteritis over five years in a pediatric hospital.
- To determine the incidence and characteristics of rotavirus infections, including hospital-acquired cases.
Summary:
- Rotavirus accounted for 13% of pediatric gastroenteritis cases.
- Seasonal peaks occurred in January, with 45.8% of infected children under six months old.
- One-third of rotavirus infections were hospital-acquired, with a 4.4% incidence during winter.
Impact:
- Provides data on rotavirus burden in a specific pediatric setting.
- Informs infection control strategies to reduce nosocomial rotavirus transmission.
- Highlights the vulnerability of infants to rotavirus infection and hospital acquisition.
Abstract:
Rotavirus is the major cause of gastroenteritis in children and the main cause of hospital acquired-infection in paediatric unit. We report the epidemiology of gastroenteritis in our hospital during five consecutive years. Rotavirus was involved in 13% of the patients. Seasonal peaks were observed in January and 45.8% of the patients were less than 6 month old. The rotavirus infection was hospital-acquired in 1/3 of the cases. During the winter period, the incidence of rotavirus nosocomial infection was 4.4%.
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