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Updated: Jul 10, 2026
07:27
Anterior Segment Organ Culture Platform for Tracking Open Globe Injuries and Therapeutic Performance
Published on: August 25, 2021
[The factors affecting visual outcome in open globe injuries]
Vuslat Pelitli Gürlü1, Haluk Esgin, Omer Benian
1Department of Ophthalmology, Medicine Faculty of Trakya University, Edirne, Turkey. gurluvuslat@yahoo.com
Summary
Open globe injuries significantly impact visual acuity, with posterior segment pathology and anterior chamber loss being key determinants of outcomes. Early detection and management are crucial for improving vision after surgical repair.
Area of Science:
- Ophthalmology
- Trauma Surgery
Background:
- Open globe injuries pose a significant threat to visual function.
- Surgical repair is critical for managing these severe ocular traumas.
Purpose of the Study:
- To identify factors influencing visual acuity after surgical repair of open globe injuries.
- To elucidate prognostic indicators for visual outcomes in trauma patients.
Main Methods:
- Retrospective analysis of 119 cases undergoing emergency surgical repair for open globe injury.
- Statistical evaluation using Chi-square test and logistic regression analysis.
- Examination of variables including age, gender, trauma type, and preoperative findings.
Main Results:
- Initial visual acuity, trauma zone, trauma type, anterior chamber loss, hyphema, vitreous prolapse, and posterior segment pathology significantly affected visual outcomes.
- Posterior segment pathology (Odds ratio=12.397) and total anterior chamber loss (Odds ratio=4.661) were strong predictors of poor visual acuity (grade 4 or 5).
Conclusions:
- Posterior segment pathology and anterior chamber loss are critical determinants of final visual acuity.
- Ophthalmoscopy and ultrasonography are essential diagnostic tools for evaluating these injuries during follow-up.
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