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Related Experiment Video

Updated: Jul 10, 2026

Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants
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Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants

Published on: June 13, 2021

Maternal depression and developmental disability: research critique.

Donald B Bailey1, Robert N Golden, Jane Roberts

  • 1RTI International, Research Triangle Park, NC 27709-2194, USA. dbailey@rti.org <dbailey@rti.org>

Mental Retardation and Developmental Disabilities Research Reviews
|November 6, 2007
PubMed
Summary

Maternal depression in families with a child with a disability is common, but research often confuses depressive symptoms with clinical depression. More rigorous studies are needed to understand and treat maternal depression effectively.

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Area of Science:

  • Psychiatry
  • Developmental Psychology
  • Family Studies

Background:

  • Maternal depression is a significant concern in families with children with disabilities.
  • Previous research has extensively studied depressive symptoms, but less so clinical depression.

Purpose of the Study:

  • To review and critique the literature on maternal depression in families of children with disabilities.
  • To identify consensus findings and methodological limitations.
  • To recommend future research directions, emphasizing the distinction between depressive symptoms and clinical depression.

Main Methods:

  • Systematic review of 42 articles on maternal depression and childhood disability.
  • Critique of research methodologies, focusing on diagnostic criteria for depression.
  • Analysis of factors associated with depressive symptoms.

Main Results:

  • Most studies assessed depressive symptoms, not clinically diagnosed depression (only 8/42).
  • Mothers of children with disabilities show higher rates of depressive symptoms and risk for clinical depression than the general population.
  • Child behavior problems, maternal stress, coping, and support are consistently linked to depressive symptoms.

Conclusions:

  • Current understanding of clinical depression in mothers of children with disabilities is limited.
  • Distinguishing between depressive symptoms and clinical depression is crucial for family support and adaptation.
  • Future research requires validated diagnostic tools and studies on effective treatments.