Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Bioplastics01:27

Bioplastics

Bioplastics derived from microbial processes present a sustainable alternative to conventional petroleum-based plastics. Among these, polyhydroxyalkanoates (PHAs), particularly polyhydroxybutyrates (PHBs), have emerged as prominent candidates due to their biodegradability and biocompatibility. These polymers are synthesized by a variety of bacteria, such as Cupriavidus necator and Pseudomonas putida, which naturally accumulate PHAs as intracellular carbon and energy reserves, especially under...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A Collagen-based Scaffold Supports Tendon-to-bone Healing After Rotator Cuff Repair: An Integrated Translational Study.

Advanced healthcare materials·2026
Same author

Evaluating the Effects of Poly(ε-Caprolactone)-Nanohydroxyapatite Composition on 3D-Printed Scaffold Structural Properties.

Journal of biomedical materials research. Part A·2026
Same author

Topographical design principles for osteochondral tissue engineering.

Bioactive materials·2026
Same author

Comparison of innovative medical devices between China and the United States.

Regenerative biomaterials·2026
Same author

Bone matrix-inspired whitlockite porous ceramic with effects of autophagy activation contributes to bone regeneration.

Bioactive materials·2026
Same author

3D Printing Colloidal Gels: Navigating the Printability Barrier.

Tissue engineering. Part C, Methods·2025

Related Experiment Video

Updated: Jul 10, 2026

A Facile and Eco-friendly Route to Fabricate Poly(Lactic Acid) Scaffolds with Graded Pore Size
13:46

A Facile and Eco-friendly Route to Fabricate Poly(Lactic Acid) Scaffolds with Graded Pore Size

Published on: October 17, 2016

Biodegradable fumarate-based polyHIPEs as tissue engineering scaffolds.

Elizabeth M Christenson1, Wafa Soofi, Jennifer L Holm

  • 1Department of Bioengineering, Rice University, Houston, Texas 77251-1892, USA.

Biomacromolecules
|November 6, 2007
PubMed
Summary

Biodegradable polyHIPEs were created using emulsion templating for tissue engineering. These scaffolds offer tunable pore sizes and high porosity, making them ideal for cell growth and tissue regeneration.

More Related Videos

Composite Scaffolds of Interfacial Polyelectrolyte Fibers for Temporally Controlled Release of Biomolecules
11:13

Composite Scaffolds of Interfacial Polyelectrolyte Fibers for Temporally Controlled Release of Biomolecules

Published on: August 19, 2015

Viability of Bioprinted Cellular Constructs Using a Three Dispenser Cartesian Printer
07:05

Viability of Bioprinted Cellular Constructs Using a Three Dispenser Cartesian Printer

Published on: September 22, 2015

Related Experiment Videos

Last Updated: Jul 10, 2026

A Facile and Eco-friendly Route to Fabricate Poly(Lactic Acid) Scaffolds with Graded Pore Size
13:46

A Facile and Eco-friendly Route to Fabricate Poly(Lactic Acid) Scaffolds with Graded Pore Size

Published on: October 17, 2016

Composite Scaffolds of Interfacial Polyelectrolyte Fibers for Temporally Controlled Release of Biomolecules
11:13

Composite Scaffolds of Interfacial Polyelectrolyte Fibers for Temporally Controlled Release of Biomolecules

Published on: August 19, 2015

Viability of Bioprinted Cellular Constructs Using a Three Dispenser Cartesian Printer
07:05

Viability of Bioprinted Cellular Constructs Using a Three Dispenser Cartesian Printer

Published on: September 22, 2015

Area of Science:

  • Biomaterials Science
  • Polymer Chemistry
  • Tissue Engineering

Background:

  • PolyHIPEs (Polymerized High Internal Phase Emulsions) offer precise control over scaffold architecture.
  • Biodegradable scaffolds are crucial for successful tissue engineering applications.

Purpose of the Study:

  • To synthesize and characterize novel biodegradable polyHIPEs for tissue engineering.
  • To investigate the effect of formulation parameters on scaffold properties.

Main Methods:

  • Emulsion templating was used to create polyHIPEs from poly(propylene fumarate) (PPF) and propylene fumarate diacrylate (PFDA).
  • Varying diluent, cross-linker concentrations, and macromer molecular weight influenced pore size and morphology.
  • Porosity was determined using gravimetric analysis.

Main Results:

  • A range of rigid, microporous polyHIPEs with interconnected pores (10-300 microm) were successfully generated.
  • Scaffold porosity ranged from 80-89%, with most exceeding 84%.
  • Formulations allowed for control over pore size and morphology.

Conclusions:

  • Emulsion templating is a viable method for producing tunable, biodegradable polyHIPEs.
  • These polyHIPEs possess suitable characteristics for advanced tissue engineering scaffolds.
  • The developed scaffolds demonstrate potential for promoting cell infiltration and tissue regeneration.