Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Number development and developmental dyscalculia.

Michael G von Aster1, Ruth S Shalev

  • 1Department of Child and Adolescent Psychiatry, German Red Cross Hospitals, Berlin, Germany. vonaster@kjpd.unizh.ch

Developmental Medicine and Child Neurology
|November 6, 2007
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Cognitive and psychiatric phenotypes of movement disorders in children: a systematic review.

Developmental medicine and child neurology·2011
Same author

Tourette syndrome-associated psychopathology: roles of comorbid attention-deficit hyperactivity disorder and obsessive-compulsive disorder.

Journal of developmental and behavioral pediatrics : JDBP·2009
Same author

The utility of a continuous performance test embedded in virtual reality in measuring ADHD-related deficits.

Journal of developmental and behavioral pediatrics : JDBP·2009
Same author

Emotional and behavioral characteristics over a six-year period in youths with persistent and nonpersistent dyscalculia.

Journal of learning disabilities·2008
Same author

ADHD and dysgraphia: underlying mechanisms.

Cortex; a journal devoted to the study of the nervous system and behavior·2007
Same author

Parenting style impacts on quality of life in children with cerebral palsy.

The Journal of pediatrics·2007
Same journal

Predictive ability of the Hammersmith Neonatal Neurological Examination for identifying severe neurodevelopmental impairment in infants born very preterm.

Developmental medicine and child neurology·2026
Same journal

Neuropathic pain in cerebral palsy and related genetic conditions: A scoping review of prevalence, characteristics, and management.

Developmental medicine and child neurology·2026
Same journal

Hammersmith Infant Neurological Examination global scores for predicting neurodevelopmental outcomes after 2 years of age: A systematic review and meta-analysis.

Developmental medicine and child neurology·2026
Same journal

Seizure worsening and sodium channel blockers in HCN1-related epilepsies: A case series.

Developmental medicine and child neurology·2026
Same journal

What is the impact of childhood-onset disability research - and what should it be?

Developmental medicine and child neurology·2026
Same journal

Sleep disturbances in children with cerebral palsy, their siblings, and parents: A qualitative descriptive study.

Developmental medicine and child neurology·2026
See all related articles

Developmental dyscalculia (DD) may stem from a genetic number sense disorder, potentially with or without comorbidities like language or attention issues. Brain imaging reveals under-activation in parietal and frontal regions in children with DD.

Area of Science:

  • Neuropsychology
  • Developmental Neuroscience
  • Cognitive Science

Background:

  • Developmental dyscalculia (DD) is increasingly viewed as a genetically influenced disorder affecting 'number sense,' the ability to grasp numerical magnitude nonverbally.
  • The development of this internal number line relies on working memory and number symbolization, suggesting potential comorbidities.
  • Epidemiological data show two-thirds of children with DD have co-occurring conditions, while one-third have pure DD, impacting their arithmetic profiles.

Purpose of the Study:

  • To explore the dual nature of developmental dyscalculia (DD) and its neuropsychological underpinnings.
  • To present a developmental model for predicting different pathways of DD.
  • To link neuroimaging findings to cognitive deficits in DD.

Main Methods:

Related Experiment Videos

  • Review of existing literature on the genetic and neuropsychological basis of DD.
  • Analysis of epidemiological data on DD comorbidities.
  • Functional magnetic resonance imaging (fMRI) studies examining brain activity in children with DD.

Main Results:

  • fMRI studies indicate under-activation in parietal (number processing) and frontal (working memory, attention) regions in children with DD.
  • A four-step developmental model is proposed, outlining the progression from core number sense to symbolic representation and working memory development.
  • The model differentiates pathways for DD based on the presence of comorbidities.

Conclusions:

  • DD can manifest as a pure number sense deficit or with comorbid conditions, influencing clinical presentation.
  • A four-step developmental model provides a framework for understanding DD pathways and informs therapeutic interventions.
  • Interventions for DD can be tailored based on the identified developmental pathway and cognitive profile.