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Updated: Jul 9, 2026

Intravascular Delivery of Biologics to the Rat Kidney
Published on: September 1, 2016
alphaPlGF: a new kid on the antiangiogenesis block
1Steele Lab of Tumor Biology, Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA. jain@steele.mgh.harvard.edu
Abstract:
An agent that blocks tumor angiogenesis, growth, and metastasis without affecting normal tissues -- whether used alone or in combination with currently approved drugs -- would change the way we treat cancer. In this issue, Fischer et al. (2007) offer compelling evidence that a monoclonal antibody against placental growth factor (PlGF), a member of the VEGF family, has such potential in mice.
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