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The type II transmembrane serine protease matriptase-2--identification, structural features, enzymology, expression

Andrew J Ramsay1, Janet C Reid, Gloria Velasco

  • 1Institute of Health and Biomedical Innovation, Queensland University of Technology, Kelvin Grove, Queensland 4059, Australia.

Frontiers in Bioscience : a Journal and Virtual Library
|November 6, 2007
PubMed
Summary

Matriptase-2 (TMPRSS6) is a serine protease with a conserved structure across mammals. Its functions are unknown but high expression in the liver suggests roles in normal and disease states.

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