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Related Experiment Videos

Microfluidic chips for cell sorting.

Pu Chen1, Xiaojun Feng, Wei Du

  • 1Division of Biomedical Photonics at Wuhan National Laboratory for Optoelectronics, Department of Systems Biology, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan 430074, China.

Frontiers in Bioscience : a Journal and Virtual Library
|November 6, 2007
PubMed
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Microfluidics-based cell sorting in micro total analysis systems (microTAS) offers advantages for single cell analysis. This review highlights recent advances in microfluidic cell sorting mechanisms and procedures for improved biological and chemical analyses.

Area of Science:

  • Biotechnology
  • Analytical Chemistry
  • Microfluidics

Background:

  • Micro total analysis systems (microTAS), or lab-on-a-chip, are rapidly advancing in biological and chemical analysis.
  • Microfluidic cell sorting is crucial for single-cell analysis, offering advantages over traditional methods.
  • Intensive research focuses on microfluidics for cell manipulation, sorting, and multi-functional integration.

Purpose of the Study:

  • To review recent advancements in microfluidics-based cell sorting techniques.
  • To emphasize the sorting mechanisms and procedures within microfluidic cell sorting.
  • To discuss evaluation criteria and future directions for microfluidic cell sorters.

Main Methods:

  • Review of recent literature on microfluidics-based cell sorting.

Related Experiment Videos

  • Analysis of cell sorting principles, strategies, mechanisms, and procedures.
  • Discussion of evaluation metrics for cell sorter performance.

    • Main Results:

    • Comprehensive overview of current microfluidics-based cell sorting techniques.
    • Detailed examination of sorting mechanisms and procedures.
    • Identification of key evaluation criteria for cell sorter success.

    Conclusions:

    • Microfluidic cell sorting is a key enabling technology for microTAS and single-cell analysis.
    • Further research into sorting mechanisms and evaluation criteria will advance the field.
    • This review provides a foundation for understanding and developing next-generation microfluidic cell sorters.