Related Experiment Video
Updated: Jul 10, 2026

Substernal Thyroid Biopsy Using Endobronchial Ultrasound-guided Transbronchial Needle Aspiration
Published on: November 10, 2014
Papillary thyroid carcinoma metastasis most probably due to fine needle aspiration biopsy. A case report
Demetrio Tamiolakis1, Chara Antoniou, John Venizelos
1Department of Cytology, Regional Hospital of Chania, Crete, Greece.
Abstract:
Implantation of cancer cells from needle biopsy has been reported in a wide range of malignancies. Fine needle aspiration biopsy has become an accepted method for assessment of thyroid nodules. Local reappearance of thyroid cancer from needle track dissemination is a rare complication of thyroid aspiration. A 45-year-old female developed local recurrence of papillary thyroid carcinoma four years after aspiration biopsy and thyroidectomy. Metastatic deposits appeared in the skin and the sternocleidomastoid muscle. The linear array and the site of metastases implied that seeding most probably resulted from the needle biopsy.

