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xBASE2: a comprehensive resource for comparative bacterial genomics.

Roy R Chaudhuri1, Nicholas J Loman, Lori A S Snyder

  • 1Centre for Systems Biology, University of Birmingham, Birmingham B15 2TT, UK.

Nucleic Acids Research
|November 7, 2007
PubMed
Summary
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xBASE 2.0 is an updated genome database for bacteriologists, enhancing bacterial comparative genomics with comprehensive data and improved search tools. This resource aids researchers in utilizing bacterial genome sequences effectively.

Area of Science:

  • Microbiology
  • Bioinformatics
  • Genomics

Background:

  • Bacteriologists require efficient tools for analyzing bacterial genome sequences.
  • Comparative genomics is crucial for understanding bacterial evolution and function.
  • Existing databases may lack comprehensive coverage or user-friendly features.

Purpose of the Study:

  • To introduce xBASE 2.0, an enhanced genome database.
  • To improve the utility of bacterial genome sequence data for laboratory-based research.
  • To facilitate comparative genomics studies in bacteriology.

Main Methods:

  • Development of xBASE 2.0 with a modularized backend.
  • Implementation of an improved user interface.
  • Integration of a taxonomy browser and full-text search functionality.

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Main Results:

  • xBASE 2.0 offers comprehensive coverage of bacterial genomes.
  • The updated interface enhances user experience and data navigation.
  • New features support powerful data retrieval and analysis.

Conclusions:

  • xBASE 2.0 provides a valuable resource for bacteriologists.
  • The database advancements support effective comparative genomics.
  • Enhanced accessibility and functionality improve the use of bacterial genomic data.