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Updated: Jul 10, 2026
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Functional Cloning Using a Xenopus Oocyte Expression System
Published on: January 30, 2016
Xenbase: a Xenopus biology and genomics resource
Jeff B Bowes1, Kevin A Snyder, Erik Segerdell
1Department of Computer Science, University of Calgary, 2500 University Drive NW, Calgary, Alberta, Canada.
Nucleic Acids Research
|November 7, 2007
Summary
Xenbase is a comprehensive database for Xenopus frogs, integrating diverse biological and genomic data. It enhances research accessibility by providing gene information, genome browsing, and BLAST services for Xenopus laevis and Xenopus tropicalis.
Area of Science:
- Amphibian genomics
- Model organism databases
- Developmental biology
Background:
- Xenopus laevis and Xenopus tropicalis are crucial model organisms in biological research.
- A centralized repository for their diverse biological and genomic data is essential for efficient research.
Purpose of the Study:
- To describe Xenbase, a comprehensive model organism database for Xenopus.
- To highlight its data integration, annotation, and accessibility features for the research community.
Main Methods:
- Data aggregation from various sources including literature, high-throughput screens, and external databases.
- Integration into specialized modules for community, literature, gene, and genomic analysis.
- Automated gene page assembly and in-house annotation.
Main Results:
- Xenbase provides integrated access to genomic and biological data for Xenopus.
- Features include Gbrowse genome browser, BLAST service, and a Xenopus gene synonym table.
- Seamless integration with external resources enhances data discoverability.
Conclusions:
- Xenbase effectively consolidates and presents extensive Xenopus data.
- It serves as a valuable resource, improving the accessibility of frog developmental and functional data for researchers worldwide.
