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Evaluation of higher order ocular aberrations in patients with keratoconus
Li Lim1, Rui Hua Wei, Wing Kwong Chan
1Singapore National Eye Centre, Singapore, PR China. lim_li@snec.com.sg
Purpose:
To describe higher order ocular aberrations in eyes with keratoconus.
Methods:
Prospective, observational, case-control study comparing higher order ocular aberrations in patients with keratoconus with control subjects with myopia.
Results:
One hundred sixteen patients with keratoconus were recruited. Data were analyzed in 35 keratoconus eyes, 38 keratoconus suspect eyes, and 166 right eyes with myopia. Mean total higher order root-mean-square (RMS) values (3rd to 5th order) were 1.73 +/- 0.71 microm in eyes with keratoconus, 0.94 +/- 0.66 microm in eyes with keratoconus suspect, and 0.49 +/- 0.16 microm in control eyes. Keratoconus eyes had greater total higher order RMS, 3rd to 5th order RMS, and RMS for all Zernike terms than those in the control group (P < .001).
Conclusions:
Keratoconus and keratoconus suspect eyes had significantly larger higher order aberrations in total higher order RMS and 3rd order RMS than control eyes.
