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Exploring the Neural Correlates of Cognitive Reappraisal in Obsessive-Compulsive Disorder Using Task-based Functional Magnetic Resonance Imaging
Published on: March 14, 2025
Symptom dimensions and cognitive-behavioural therapy outcome for pediatric obsessive-compulsive disorder
E A Storch1, L J Merlo, M J Larson
1Department of Psychiatry, University of Florida, Gainesville, FL 32610, USA. estorch@psychiatry.ufl.edu
Acta Psychiatrica Scandinavica
|November 8, 2007
Summary
Pediatric obsessive-compulsive disorder (OCD) symptom subtypes did not significantly impact treatment response rates to cognitive-behavioural therapy (CBT). Most children and adolescents showed improvement, regardless of their specific OCD symptoms.
Area of Science:
- Child and Adolescent Psychiatry
- Behavioral Therapy Research
- Mental Health Treatment
Background:
- Obsessive-compulsive disorder (OCD) is a common childhood psychiatric condition.
- Cognitive-behavioural therapy (CBT) is a primary treatment for pediatric OCD.
- Understanding treatment response across OCD symptom subtypes is crucial for personalized care.
Purpose of the Study:
- To investigate the association between OCD symptom subtypes and treatment response in pediatric patients.
- To determine if specific OCD symptom presentations predict outcomes in family-based CBT.
Main Methods:
- Ninety-two pediatric patients (7-19 years) with OCD received 14 sessions of family-based CBT.
- Assessments included the Children's Yale-Brown Obsessive-Compulsive Scale (CY-BOCS) and Clinical Global Impression (CGI) scales.
- Treatment response was evaluated based on CY-BOCS scores, remission status, and CGI ratings.
Main Results:
- Seventy-six percent of participants were classified as treatment responders.
- A trend towards improved treatment response was observed in patients with aggressive/checking symptoms.
- Higher scores in aggressive/checking dimensions predicted greater CGI-Severity change, but not CY-BOCS score differences.
Conclusions:
- Pediatric OCD symptom subtypes do not substantially influence overall response rates to CBT.
- Family-based CBT appears effective across various OCD presentations in children and adolescents.
- Further research may explore nuanced treatment effects for specific symptom dimensions.
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