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Updated: Jul 10, 2026

Solubility of Hydrophobic Compounds in Aqueous Solution Using Combinations of Self-assembling Peptide and Amino Acid
Published on: September 20, 2017
Two salts of 5-sulfosalicylic acid and 3-aminopyridine
Xiang Gao Meng1, Chun Shan Zhou, Li Wang
1Key Laboratory of Pesticide and Chemical Biology, Ministry of Education, College of Chemistry, Central China Normal University, Wuhan 430079, People's Republic of China. mengxianggao@mail.ccnu.edu.cn
Abstract:
5-Sulfosalicylic acid (5-SSA) and 3-aminopyridine (3-APy) crystallize in the same solvent system, resulting in two kinds of 1:1 proton-transfer organic adduct, namely 3-aminopyridinium 3-carboxy-4-hydroxybenzenesulfonate monohydrate, C(5)H(7)N(2)(+).C(7)H(5)O(6)S(-).H(2)O or 3-APy.5-SSA.H(2)O, (I), and the anhydrous adduct, C(5)H(7)N(2)(+).C(7)H(5)O(6)S(-) or 3-APy.5-SSA, (II). Both compounds have extensively hydrogen-bonded three-dimensional layered polymer structures, with interlayer homo- and heterogeneous pi-pi interactions in (I) and (II), respectively.
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