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Prevention of allergic respiratory disease in infants: current aspects and future perspectives

Patrick G Holt1, Peter D Sly

  • 1Division of Cell Biology, Telethon Institute for Child Health Research, Centre for Child Health Research, The University of Western Australia, Perth, Western Australia, Australia. patrick@ichr.uwa.edu.au

Current Opinion in Allergy and Clinical Immunology
|November 9, 2007
PubMed

Insights

Preventing severe atopic diseases like asthma in children is a growing research area. Early interventions targeting immune function and infections show promise for future prophylaxis strategies.

Area of Science:

  • Pediatric Allergy and Immunology
  • Immunology
  • Preventive Medicine

Background:

  • Severe atopic diseases, such as atopic asthma, are a significant concern in pediatric allergy.
  • There is a growing research focus on the primary and secondary prevention of these conditions.

Purpose of the Study:

  • To review the rationale behind preventive strategies for atopic diseases in children.
  • To discuss recent advancements in the development and testing of potential preventive interventions.

Main Methods:

  • Review of current literature on preventive strategies for atopic diseases.
  • Analysis of treatments targeting immune function, allergen-specific immunomodulation, and viral infections.

Main Results:

  • Key areas of focus include enhancing general immune functions.
  • Allergen-specific immunomodulation and managing respiratory viral infections in early childhood are crucial.
  • Potential and existing treatments are being evaluated.

Conclusions:

  • The scientific basis for prophylaxis of atopic diseases through early intervention in young children is strengthening.
  • Significant progress in this field is anticipated in the near future.
Abstract

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