Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Anthelminthic Agents01:15

Anthelminthic Agents

Anthelmintic drugs differ significantly from antiparasitic therapies targeting protozoa, primarily due to differences in parasite biology. Whereas most protozoal treatments act on proliferating cells, anthelmintics are typically directed against mature, nonproliferative helminths. The therapeutic approach considers the helminth's reliance on neuromuscular coordination, glucose metabolism, and microtubular integrity for survival, reproduction, and localization within the host. Most anthelmintics...
Hybridoma Technology01:31

Hybridoma Technology

Hybridoma technology is used for the large-scale production of monoclonal antibodies. Monoclonal antibodies bind to only a single antigenic determinant or epitope. Such antibodies are used in research, diagnostics, and disease therapy. The hybridoma technology established in 1975 by Georges Köhler and Cesar Milstein was awarded the Nobel Prize in Medicine in 1984 for revolutionizing research and therapy.
Hybridoma Selection
Commonly used fusion techniques — electroporation, polyethylene glycol...
Modern Molecular Taxonomy01:29

Modern Molecular Taxonomy

Advancements in molecular biology have revolutionized the identification and characterization of bacteria, with multiple methods leveraging DNA sequencing for enhanced precision. As sequencing technologies improve and costs decline, these approaches are increasingly used in clinical, environmental, and evolutionary studies.Multilocus Sequence Typing (MLST) examines several housekeeping genes, essential chromosomal genes encoding cellular functions, to distinguish strains. Approximately...
Toxoplasmosis01:28

Toxoplasmosis

Toxoplasmosis, a zoonotic disease caused by the protozoan Toxoplasma gondii, poses significant public health challenges globally due to its high seroprevalence and varied clinical manifestations. As an obligate intracellular parasite, T. gondii can infect all warm-blooded vertebrates, but felids are its only definitive hosts, shedding unsporulated oocysts into the environment. Humans typically acquire the infection through ingestion of tissue cysts in undercooked meat or oocysts from...
In-vitro Mutagenesis01:16

In-vitro Mutagenesis

To learn more about the function of a gene, researchers can observe what happens when the gene is inactivated or “knocked out,” by creating genetically engineered knockout animals. Knockout mice have been particularly useful as models for human diseases such as cancer, Parkinson’s disease, and diabetes.

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A cohort study of obese patients with moderate-to-severe psoriasis using biological medicines in Catalonia, Spain.

Dermatology reports·2026
Same author

Haploidentical transplant, gene therapy, and standard care in sickle cell disease: a cost-effectiveness analysis.

Blood·2026
Same author

Increasingly Reversible Na/Cl<sub>2</sub> and Li/Cl<sub>2</sub> Batteries.

Journal of the American Chemical Society·2026
Same author

Barriers to effective first-line treatment for women with iron deficiency.

Expert review of hematology·2026
Same author

Cost-effectiveness of iron deficiency screening in pregnancy across ferritin-based thresholds.

Blood advances·2026
Same author

The Prevalence of Fibromyalgia in the General Population and At-Risk Subpopulations: A Systematic Review and Meta-Analysis.

Anesthesia and analgesia·2026

Related Experiment Video

Updated: Jul 10, 2026

Navigating MARRVEL, a Web-Based Tool that Integrates Human Genomics and Model Organism Genetics Information
09:37

Navigating MARRVEL, a Web-Based Tool that Integrates Human Genomics and Model Organism Genetics Information

Published on: August 15, 2019

WormBase 2007.

Anthony Rogers1, Igor Antoshechkin, Tamberlyn Bieri

  • 1Sanger Institute, Wellcome Trust Genome Campus Hinxton, Cambridgeshire CB10 1SA, UK.

Nucleic Acids Research
|November 10, 2007
PubMed
Summary

WormBase is a key database for Caenorhabditis elegans research, integrating genomic and functional data. It supports the wider biomedical and bioinformatics communities by providing comprehensive nematode information and advanced tools.

More Related Videos

Investigating the Spreading and Toxicity of Prion-like Proteins Using the Metazoan Model Organism C. elegans
12:57

Investigating the Spreading and Toxicity of Prion-like Proteins Using the Metazoan Model Organism C. elegans

Published on: January 8, 2015

Deciphering and Imaging Pathogenesis and Cording of Mycobacterium abscessus in Zebrafish Embryos
10:38

Deciphering and Imaging Pathogenesis and Cording of Mycobacterium abscessus in Zebrafish Embryos

Published on: September 9, 2015

Related Experiment Videos

Last Updated: Jul 10, 2026

Navigating MARRVEL, a Web-Based Tool that Integrates Human Genomics and Model Organism Genetics Information
09:37

Navigating MARRVEL, a Web-Based Tool that Integrates Human Genomics and Model Organism Genetics Information

Published on: August 15, 2019

Investigating the Spreading and Toxicity of Prion-like Proteins Using the Metazoan Model Organism C. elegans
12:57

Investigating the Spreading and Toxicity of Prion-like Proteins Using the Metazoan Model Organism C. elegans

Published on: January 8, 2015

Deciphering and Imaging Pathogenesis and Cording of Mycobacterium abscessus in Zebrafish Embryos
10:38

Deciphering and Imaging Pathogenesis and Cording of Mycobacterium abscessus in Zebrafish Embryos

Published on: September 9, 2015

Area of Science:

  • Nematode genomics and bioinformatics
  • Model organism databases

Background:

  • WormBase is the primary public database for Caenorhabditis elegans.
  • C. elegans is a vital model system for biological and biomedical research.

Purpose of the Study:

  • To describe the scope and features of WormBase.
  • To highlight its importance for C. elegans researchers and the broader scientific community.

Main Methods:

  • Data integration from ACeDB and other sources.
  • Development of genomic, anatomical, and functional information modules.
  • Enhancement of search, display, and cross-species comparison tools.

Main Results:

  • WormBase now encompasses genomic, anatomical, and functional data for C. elegans, other Caenorhabditis species, and nematodes.
  • Improved tools facilitate research and utilization of other nematode genome sequences.
  • Expanded ontologies and cross-species comparisons enhance research capabilities.

Conclusions:

  • WormBase is an indispensable resource for C. elegans research and the wider biomedical and bioinformatics fields.
  • The database's comprehensive data and advanced features empower scientific discovery in nematodes.