Related Experiment Video
Updated: Sep 11, 2026

Ex Vivo Infection of Human Lymphoid Tissue and Female Genital Mucosa with Human Immunodeficiency Virus 1 and Histoculture
Published on: October 12, 2018
[HIV infections. Problems of morphologic diagnosis]
Abstract:
Considerable ultrastructural changes in the lymphoid cells of immunocompetent organs as well as in the epithelial and stromal cells of the rectum--the organ of the first contact with the virus in some cases--are found in HIV-infection. These alterations are of a quantitative nature and are the indications of important disturbances of the water-salt and protein metabolism. Changes in the lymphocytes and plasmacytes of the rectum lamina propria result in the damage to local immune defense. The presence of tubuloreticular and tubulo-annular structures in various cells of the rectum and lymphoid organs which are clearly seen in the biopsy material is most likely a characteristic sign of HIV-infection at its terminal stage.
More Related Videos
13:13Single-cell Quantitation of mRNA and Surface Protein Expression in Simian Immunodeficiency Virus-infected CD4+ T Cells Isolated from Rhesus macaques
Published on: September 25, 2018
07:21Processing of Bronchoalveolar Lavage Fluid and Matched Blood for Alveolar Macrophage and CD4+ T-cell Immunophenotyping and HIV Reservoir Assessment
Published on: June 23, 2019
Related Concept Videos
Retrovirus Life Cycles
Pulmonary Tuberculosis I
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Cytomegalovirus Disease
Genital Herpes
Cryptococcal Meningitis
Inhibitors of Virion Maturation and Assembly