Discovery of motifs in promoters of coregulated genes
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Updated: Jul 10, 2026

Using SCOPE to Identify Potential Regulatory Motifs in Coregulated Genes
Published on: May 31, 2011
Olivier Sand1, Jacques van Helden
1Service de Conformation des Macromolécules, Biologiques et de Bioinformatiques, Université Libre de Bruxelles, Belgium.
Abstract:
We present a method to predict cis-acting elements by detecting over-represented motifs in promoters of a set of coregulated genes (single-genome, multigenes approach). The method has been used successfully to detect regulating elements in bacteria and yeast. It can be used with higher organisms as well, but with a loss in reliability of the predictions. A web interface is available at the Regulatory Sequence Analysis Tools site (http://rsat.scmbb.ulb.ac.be/rsat/).
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