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Analysis of human immunodeficiency virus matrix domain replacements

Isabel Scholz1, Amelia Still, Tenzin Choesang Dhenub

  • 1Department of Molecular Microbiology and Immunology, Oregon Health & Sciences University, Portland, OR, USA.

Virology
|November 13, 2007
PubMed
Summary

The matrix (MA) domain of HIV-1 Gag is crucial for viral assembly. While alternative membrane-binding domains can facilitate virus-like particle release, they impair infectious virus production and core formation.

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